Vocal Fold Wound Healing
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Vocal Fold Wound Healing From Basic Science to Clinical Care by Ryan C., Ph.D. Branski

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Published by Plural Publishing .
Written in English


  • Speech & language disorders & therapy,
  • Medical,
  • Medical / Nursing,
  • Audiology & Speech Pathology,
  • Medical / Audiology & Speech Pathology,
  • Otolaryngology

Book details:

The Physical Object
Number of Pages192
ID Numbers
Open LibraryOL12493910M
ISBN 101597560596
ISBN 109781597560597

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Development of novel vocal fold (VF) therapeutics is limited by a lack of standardized, meaningful outcomes. We hypothesize that automated microindentation‐based VF biomechanical property mapping matched to histology permits quantitative assessment. Study Design. Ex vivo. MethodsAuthor: Gregory R. Dion, Gregory R. Dion, Teja Guda, Shigeyuki Mukudai, Renjie Bing, Jean‐Francois Lavoie, R. These vocal folds showed increased hepatocyte growth factor (HGF)‐positive cells within the wound and improved wound healing compared with sham‐treated folds. Conclusion: Circulating MSCs can migrate to vocal fold wound sites and upregulate the expression of HGF during wound healing; thus, they are considered to play a significant role in Cited by: Objective: To assess the potential wound-healing effects of PBM on the vocal folds via in vivo and in vitro experiments. Materials and methods: In in vitro study, vocal fold fibroblasts (VFFs) were irradiated under a diode laser with wavelength of nm at energy density of 8 J/cm by: 1. This analogy and accompanying graphic provide a framework for a unique perspective on wound healing. For the sake of simplicity, let us assume that the vocal fold is a fence, and instead of a Volkswagen Beetle, the trauma is surgical excision of a vocal fold lesion.

Vocal fold scarring is the greatest cause of poor voice after vocal fold injury. Scarring causes a disruption of the viscoelastic layered structure of the lamina propria, an increase in stiffness of the vibratory structure, and glottic incompetence. Current treatments for this complex condition are inconsistent and often produce suboptimal results. Diagnosis and Treatment of Voice Disorders, now in its fourth edition, continues to serve as a definitive reference for students and professionals in the fields of otolaryngology, speech-language pathology, voice and singing, and related -eight chapters- illustrated with color photos, dyed slides, and black and white figures are divided into three parts: basic sciences, clinical. Platelet-rich plasma (PRP) is a reliable and has low side-effect profile and has beneficial effects on wound healing. Its investigatory effects on wound-healing process were shown on various tissues. The aim of the present study was to evaluate effectiveness of PRP application on scar tissue of acute vocal fold .   Cutaneous wound healing has been well documented, and data pertaining to vocal fold scarring also exists. A histologic study of human scarred vocal folds reported that excessive and disorganized collagen deposition was observed in most cases that had undergone deep resection of the lamina propria, whereas collagen deposition was mild and well.

  Laryngeal secretions were suctioned from the surface of the vocal folds immediately before, immediately after, and 24 hours after the acupuncture. The protein concentration levels of wound‐healing–related cytokines (interleukin [IL]‐1β and IL‐10) .   In the intervening years, the art of delivering various therapy techniques, coupled with the science of vocal fold wound healing, have provided speech-language pathologists who specialize in voice a new foundation on which voice therapy is predicated and has allowed clinicians and their elite voice patients to expect epithelial vocal fold. Extensive or excessive vocal fold scarring can also occur from non-laser surgery of the vocal folds performed with poor surgical technique, for example “vocal cord / vocal fold stripping”. Other complicating factors of voice surgery resulting in vocal fold scar can be premature or excessive early voice use that hinders the normal healing. We histologically evaluated the effects of dexamethasone sodium phosphate infiltration on acute vocal fold wound healing in rabbits 3 and 7 days after surgically induced injury by quantification of the inflammatory reaction and collagen deposition. Methods: A standardized surgical incision was made in the vocal folds of 12 rabbits, and mL.